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5.2.2 Limitations due to the disease The pathophysiology of mutations or mechanisms underlying the neuronal pathology of mitochondrial diseases is still unknown in most patients, which makes it difficult to interpret the mitochondrial or neural readout in pharmacological screenings

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[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Nandi A., Yan L.-J., Jana C.K., Das N