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Description
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While in vivo models of Gclc knockout mice have had limited success, future studies could investigate this relationship with either Gclc heterozygous mice or wild type mice treated on the one hand with BSO to pharmacologically block GCLC and on the other hand with exogenous glutathione
Many studies were terminated due to a change in standard of care or, more often, because of poor accrual

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Protocol implementation for acute sprains ideally begins as soon as possible after injury, though benefits are still observed when starting later
