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Gastroenterology 124, 327334 (2003)

Melanotan 2 was first synthesized in the 1990s, building on the earlier work that produced Melanotan 1

Nitric oxide scavenging by hydroxocobalamin may account for its hemodynamic profile

C-MET927-LZ c-MET (amino acids 1927) followed by a GGGGS linker, a GCN4 zipper sequence (RMKQL EDKVE ELLSK NYHLE NEVAR LKKLV GER), HR3C, Tsi3 tag, and His6 tag, was cloned into the pEZT-BM vector (Supplementary Table 1)
