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Description
The lactylation of K62 on pyruvate kinase M2 (PKM2), a crucial enzyme in glycolysis, inhibits its transition from tetramer to dimer and enhances its pyruvate kinase activity, thereby suppressing inflammatory metabolic adaptation in pro-inflammatory macrophages
By making the immune response primarily Th2, it was possible to considerably lessen the UA levels in diabetic mice (98)
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During the CS-induced ER stress, CRT acts as an eat me signal for surrounding phagocyte [110]
Thuillier, A
