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Consequently, neuroinflammation in multiple sclerosis originates from a chronic pro-inflammatory state caused by intrinsic metabolic defects in macrophages, while post-stroke inflammation emphasizes the dynamic transition of polarization phenotypes during the acute phase

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Note, the occlusion/occlusion-like syndromes [18,19,20,21,22,23,24,25,26,27,28,29,30] include, permanent major vessel occlusion or permanent compression

Imbalanced redox states are increasingly recognized as underlying factors in major diseases, including cancers, neurodegenerative conditions, heart disease, and metabolic disorders [113]