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Description
HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction
Significant fertility results can take months
Notably, many of these pathways are involved in lipid and energy metabolism, which are critical to cellular function and overall metabolic health (Germain et al., 2020
The lethal dose threshold (LD1) was never achieved in animal safety studies meaning researchers could not identify a dose lethal to 1% of test subjects
doi:10.1038/srep08506
