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Developmental changes in trak-mediated mitochondrial transport in neurons

Enzymatic testing Because there is no specific substrate for LCHAD, its activity is determined in the backward reaction by measuring 3-ketopalmitoyl-CoA dehydrogenase activity (LCHAD+SCHAD activity) in the presence and absence of a powerful LCHAD inhibitor (N-ethylmaleimide)

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Methods: The researchers from Florida Atlantic University, had test subjects randomized to placebo or glycine propionyl-l-carnitine supplementation