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Suh HJ, Yoon SH, Yu KS, Cho JY, Park SI, Lee E et al

Ethics statement The studies involving humans were approved by Comit de tica Humana, Facultad de Ciencias Mdicas, Universidad de Buenos Aires review board ethical committee (Number: RESCD2023872)

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We demonstrate in a humanised FcRn/albumin double transgenic mouse model (AlbuMus) the ability to tune half-life based on the albumin sequence fused with a BiTE-like bispecific (anti-EGFR nanobody x anti-CD3 scFv) light T-cell engager (LiTE) construct [(t 0.6 h (Fc-less LiTE), t 19 hours (Albu-LiTE-NB), t 26 hours (Albu-LiTE-WT), t 37 hours (Albu-LiTE-HB)]