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When there is thiamine deficiency, the thiamine dependent enzyme alphaketoglutarate dehydrogenase (KGDH) will not be activated and will result in damage of the mitochondria and eventually cause cell death 4

The 6-OHDA rats exhibited significant increases in GABA levels and decreases in glutamate and N-acetyl-aspartate (NAA) levels in the ipsilateral hemisphere compared with the contralateral side

For enumeration of organ CFUs post-infection, we performed two independent experiments with at least 6 mice/group per experiment, and statistical analysis to detect significant differences in organ CFUs in each mice group was performed using using unpaired t-test, unless indicated otherwise

Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1

doi: 10.1161/01.CIR.90.6.2853