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It was found that the combined and individual treatment with EGCG and gefitinib inhibited the metastatic ability of CAL-27 cells, which was further accomplished by suppressing the expression level of p-EGFR protein and phosphorylation of ERK, JNK, p38, MMP-2 and AKT proteins [49]
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Imatinib, also a TK inhibitor, will be compared to methylprednisolone in a short-course proof-of-concept study
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