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Davis et al., 2013

More serious B12 deficiencies have the potential to impair heart and neurological function, leading to a wide range of serious symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia and changes in reflexes

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This is because digestive enzymes, which are more active during meals, readily break down glutathione

From previous investigations, a therapeutic dosage of different authorized DPP-IV inhibitors led to a two- to threefold raise in endogenous GLP-1 concentration without any inherent hypoglycemia risk and a favorable safety profile ( Figure 2 )