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Journal of Molecular Evolution

As always, more work is needed to understand the physiological interactions of kratom alkaloids in the course of further development as potential therapeutics

Inflammasomes promote the maturation and secretion of the cytokine precursors pro-IL-1 and pro-IL-18 in the process of innate immune defense by inducing the activation of caspase-1, thereby triggering an inflammatory response

The crosstalk between these cells is a crucial link in the chain of events that transforms toxic exposures into neurological symptoms