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A minimum of 8 weeks appears necessary to observe meaningful changes in chronic conditions, with 10 to 12 week cycles common

10.1371/journal.pone.0024566 PLoS One 74 GarmanR.JenkinsL.SwitzerR.IIIBaumanR.TongL.SwaugerP.et al (2011)

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J.2008Aggressive infantile embryonal tumors, 57
It may also help to focus on getting the vitamins from food instead, start with a very low dose, and be sure to use a reputable supplement manufacturer
