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Panels 2 and 4 show electron-dense granules in the perinuclear cistern (black arrowheads)

Evidence also suggests that it may raise the levels of nerve growth factor and increase the activity of acetylcholine, a neurotransmitter that is critical to healthy brain function and is substantially lost in Alzheimer's disease [2]

10.1056/NEJMra0801082 51 GallandL

Subjective dental examination of the oral cavity A medical history of subjective oral complaints was taken including an assessment for dry mouth, pain and burning in the oral cavity, pain and burning of the tongue, pain at the corners of the mouth, unpleasant breath odor, gum bleeding, dysphagia and taste disturbances
