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During lipid peroxidation, cyclic guanosine monophosphate (cGMP) is elevated, along with the downregulation of cyclic adenosine monophosphate (cAMP) concentration, leading to accelerated proliferation of epidermal cells in psoriasis ( Extensive experiments are proving that various subsets of T cells, including Th1, Th2, Th17, and regulatory T cells (Treg cell), as well as related cytokines, such as TNF-, IFN-, IL-23, and IL-17, engage in the pathogenesis of psoriasis (Hartwig et al., 2018)

According to the NIH Office of Dietary Supplements, B12 plays a key role in: Making red blood cells and preventing megaloblastic anemia Maintaining healthy nerve function and the myelin sheath that protects nerves DNA synthesis Supporting brain function and preventing cognitive decline Converting food into energy (cellular metabolism) Because B12 is found almost exclusively in animal products meat, fish, dairy, and eggs certain groups of people are at much higher risk of deficiency than others