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Description
Tumor length and width were measured using digital calipers, then the tumor size (volume) was calculated using the formula: 0.5 tumor width (cm) length (cm) 2

Primary pain in ALS includes neuropathic pain and pain due to spasticity or cramps, whereas secondary pain is mainly nociceptive and may appear as muscle weakness and atrophy progress [83]

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Results A total of 23 studies were included in the systematic review, with 7 studies involving 426 participants being meta-analyzed
