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Description
It has been proposed that the circulating peptide could access the brain via the ARC and exert its anorectic actions through indirect activation of pro-opiomelanocortin (POMC) neurons in the hypothalamus and through the blocking of fasting ghrelin levels

However, exceeding 5000 IU weekly increases risks without proportional benefits for most users

Recommended Dosage - 1000mg once daily on an empty stomach to improve bioavailability

writingoriginal draft preparation, J.D., S.A., Y.M., K.T., F.H., M.B., S.K

KashinoIKochiTImamuraFEguchiMKuwaharaKNanriAet al