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627 Traditionally, MDD was attributed to neurotransmitter alterations or brain-derived neurotrophic factor disorders

The adrenergic-induced ERK3 pathway drives lipolysis and suppresses energy dissipation

Meanwhile, GnRH antagonists such as relugolix and linzagolix rapidly suppress ovarian hormone production, leading to fibroid size reduction and symptom relief, with ongoing studies assessing their long-term safety and optimal dosing strategies