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If left untreated, Vitamin B12 deficiency can progress to pernicious anemia, a condition that can cause extensive nervous system damage and become life-threatening

2022 Jun;80(6):586-592

In this instance, inferior caval vein and superior mesenteric vein demonstrated normal vessel presentation and azygos vein is recovered to serve as a rescuing pathway with direct delivery to the superior caval vein

A small-molecule or peptide insulin-mimetic that activated IR without those constraints especially one with oral or extended-release options would change the practical economics of type 1 and insulin-dependent type 2 diabetes care, particularly outside high-income countries

Further research may shed more light on the complex relationship between B12 and metabolism