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TMAO can promote the occurrence and development of AS by activating the inflammatory cascade, increasing the risk of thrombosis, promoting the formation of foam cells, and reducing the metabolism of cholesterol (Figure 1)

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Diez-Fernandez C, Hberle J (2017) Targeting CPS1 in the treatment of Carbamoyl phosphate synthetase 1 (CPS1) deficiency, a urea cycle disorder

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