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Autophagy in the pathogenesis of disease

In the hippocampus, adult neurogenesis occurs in the subgranular zone of the dentate gyrus (111, 112) and is a complex process that involves the proliferation of neural stem cells and progenitor cells (Type 2a, 2b and 3 cells) (113115), the differentiation of neuroblasts into granular neurons through the stadium of immature granular neurons (IGNs), and the integration of new neurons into preexisting circuits in the dentate gyrus (116, 117)

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Excessive calorie intake, especially within a Western-style diet, promotes gut dysbiosis, inflammation, and obesity [52]

Adems, la mayora de las investigaciones existentes tienen bastante antigedad, por lo que deberan llevarse a cabo ms estudios para profundizar sobre los efectos de este suplemento