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Storage Store below 6C in a cool, dry place After reconstitution, refrigerate and use promptly For research and laboratory use only

The R248W and R273H mutations attribute Mre11 nuclease-binding capacity to the p53 protein to prevent association of the Mre11-Rad50-NBS1 (MRN) complex with DNA double-strand breaks, thereby impairing ataxia-telangiectasia mutated (ATM) activation and the DNA damage response (Calheiros et al

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Indeed, in normal human plasma three forms of SOD are found with the lowest amount of SOD1 (5.6-35.5 ng/ml), somehow higher amount of SOD2 (47-150 ng/ml) and even more SOD3 (79-230 ng/ml