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In addition, it is reported that in a human sepsis model, -glucan inhibits the expression of immune response gene 1 (IRG1), thereby downregulating the synthesis of itaconate and increasing the expression of succinate dehydrogenase (SDH) ( Figure 3 )

10.1016/S0168-8278(02)00108-3 64 GescherA
Early hydration improvements may appear within 1 to 2 weeks
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Akinwusi 2013)
