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10.1016/j.healun.2004.02.009 197
Yet another compound, Honokiol (HKL), has been shown to protect against doxorubicin-induced cardiotoxicity by activating SIRT3, which helps reduce ROS production, prevent mitochondrial fragmentation, and promote mitochondrial fusion 187
, & Miller, G
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Thymidine analogs, such as the BrdU and EdU we used here, mark only a subset of proliferating cells, so it is possible that further or fewer differences would be observed if all proliferating cells were labeled (with a mitotic marker such as PCNA or MCM2) and assessed
