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Arch Toxicol 97(10):27852798

In general, the procedure is performed by first making a small incision in the natural crease under the chin, which allows the doctor to remove any excess fat above the muscle
Valutazione dell'associazione di estratto di Kava-Kava e terapia ormonale sostitutiva nel trattamento d'ansia in postmenopausa

Would surmise this has something to do with blood-flow/circulation then

It's really aimed at replacing something that's present in youth and then tends to dissipate as we get older, that is the thymus and related peptides from the thymus
