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In 2000, a grade 3a, double-blind, crossover, self-controlled trial (N = 24 LOE 3b) showed improvement in some clinical measures with a daily dose of 2000 mg of LC in patients with cerebellar ataxia, but there was only one report that was not of high enough grade to show the effect of LC supplementation in patients with ataxia

( 10.3109/01485019508987833) [DOI] [PubMed] [Google Scholar] Shekhawat PS, Sonne S, Carter AL, Matern D, Ganapathy V.2013

Effects of L-carnitine administration on left ventricular remodeling after acute anterior myocardial infarction: the L-Carnitine Ecocardiografia Digitalizzata Infarto Miocardico (CEDIM) trial

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