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Rouhier et al , 2009)

Among the GSH-requiring enzymes, GPX4 reduces phospholipid hydroperoxide to corresponding alcohol and is one of the most potent enzymatic suppressors of ferroptosis [30,31]

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4 The ferroptosis-immune-metabolic axis in COPD The interplay between ferroptosis, immune dysregulation, and metabolic rewiringcollectively termed the ferroptosis-immune-metabolic axisis a central driver of COPD pathogenesis

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