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102,103 These properties have prompted their evaluation in various noninfectious diseases, including neurological disorders, cancer and complex inflammatory conditions like ARDS and tissue damage

DFX is also orally available and highly protein-bound (Gottwald et al., 2020), which potentially limits the efficacy of BBB penetration

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contributed to conceptualization, data curation, formal analysis, investigation, methodology, project administration, resources, validation, and writing-review and editing and was responsible for funding acquisition

Under these conditions, mitochondrial dysfunction will compromise metabolic performance in association with increased reactive oxygen species (ROS) generation