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The researchers confirmed the fundamental role of oxidative stress and neurovascular unit in the pathogenesis of ALS

Cicerchi C, Li N, Kratzer J, Garcia G, Roncal-Jimenez CA, Tanabe K, Hunter B, Rivard CJ, Sautin YY, Gaucher EA, Johnson RJ, Lanaspa MA (2014) Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids

Play a key role in protein synthesis

2013;19:E4553

PMID 25985235
