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Abbreviations BMP: bone morphogenetic protein CMap: Connectivity Map COPD: chronic obstructive pulmonary disease CT: computed tomography DLCO: diffusing capacity of carbon monoxide DMEM: Dulbecco's modified Eagle's medium ECM: extracellular matrix FBS: fetal bovine serum FDR: false discovery rate FEV 1 : forced expiratory volume in 1 second FVC: forced vital capacity GOLD: Global Initiative for Chronic Obstructive Lung Disease GSEA: Gene Set Enrichment Analysis Lm: mean linear intercept PBS: phosphate-buffered saline TGF: transforming growth factor Vv: volume fraction

Combination studies exploring dual amylin/incretin approaches are an active area of scientific investigation

We observed significantly increased deacetylase activity of both SIRT1 and SIRT3 in the liver and spleen of mice treated with Ab68, but not with the non-inhibitory anti-CD38 antibody Ab69 (Fig

[DOI] [PubMed] [Google Scholar] 143.Amic F., Drmic D., Bilic Z., Krezic I., Zizek H., Peklic M., Klicek R., Pajtak A., Amic E., Vidovic T., et al
