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IHC and RT-qPCR analysis indicated that genistein significantly upregulated AQP5 expression in submandibular glands of NOD/LtJ mice, approaching the levels of AQP5 expression in ICR mice (Fig

Animal experiments Four-week-old male BALB/C nude mice were purchased from the animal center of Changsheng Biotechnology (Liaoning, China), and kept in a specific pathogen-free condition and randomly divided into groups

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