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Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimers disease neurons
In contrast, in AMYRs bound to rAmy 15 or the pramlintide analogue, San385 16 , an Asn at the equivalent peptide position (N14 rAmy ) adopts an upward rotamer that is exposed to the solvent environment and forms a H-bond with the backbone of L291 ECL2 (Fig
Nutrients 13 (4), 1318
This prevents denaturation from forceful impact
Within the brain, deiodinase enzymes modulate local hormone availability (56)
