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Hep-G2 cells with MIA3 overexpression were subjected to RNA-seq, and the downstream target gene CHAC1 (glutathione-specific -glutamyl cyclotransferase 1) was selected according to the results of the volcano map of gene enrichment

Vitamin B12 is a foundational nutrient for energy production, nervous system function, red blood cell synthesis, and fat metabolism

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However, as we get older, melanin levels begin to decline, resulting in the development of hyperpigmentation
