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The net effect: adipocytes become metabolically sluggish, oxidizing less fat, storing more energy, and resisting signals that would normally promote energy expenditure

In summary, the pro-inflammatory transcriptional profile observed in leukocytes from patients with moderate and severe COVID-19 was clearly attenuated by vitamin B12, with no adverse effects predicted from these results

doi:10.3389/fncel.2020.00164

However, in patients treated with diclofenac and glucocorticoids, the risk of peptic ulcer and gastrointestinal bleeding may increase, so special attention should be given in case of prolonged treatment, even in the absence of serious gastrointestinal symptoms

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