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6 Beyond its well-characterized COX-dependent mechanisms, aspirin also engages in COX-independent pathways

The distribution of cytochrome P-450-mediated drug oxidation and glutathione in periportal and perivenous rat hepatocytes after phenobarbital treatment

Before staining, slides were thawed to room temperature for 30 min and then fixed in 10% neutral buffered formalin for 20 min, rinsed in double-distilled water, followed by rinsing in 60% isopropanol before being placed in working ORO-isopropanol stain (Rowley Biochemical, H-503-1B) for 5 min

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Similarly, the abstraction of a hydrogen on carbons 8 and 11 of OA generate 8-HpODA, 9-HpODA, 10-HpODA, and 11-HpODA
