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Recombinant human GPX4 alleviated ISO-induced myocardial ischemia injury [250]

Appl Microbiol Biotechnol 97(20):91559164

Glycine or glycine-based treatments [e.g., serine, trimethylglycine (betaine) and a glycine-based tripeptide, DT-109] lowered hepatic steatosis, inflammation and fibrosis as well as atherosclerosis in various rodent models (83, 195, 227) and humans (199) through mechanisms involving hepatic GSH biosynthesis, enhanced fatty acid utilization, suppression of proinflammatory/fibrotic responses and modulation of the gut microbiome

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