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Depending on pH conditions, CD38 catalyzes the conversion of NAD + to adenosine (ADO), a mediator of calcium signaling that promotes tumor survival and immune evasion

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International Journal of Cardiology 2013;169:8994

Observed effects in human trials Reported adverse events across the IV and oral trials included headache, fatigue, dizziness, nasopharyngitis, diarrhea, flatulence, increased appetite, nausea, and back pain

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