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However, with physiologic HNE concentrations, induction of GCLC required Nrf2 signaling (Zhang et al., 2007)

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Since the peptide promotes blood vessel formation, questions arise about whether it could support tumor growth in people with existing cancers

At physiological pH, cytochrome c has a net positive charge (+8), establishing an electrostatic bond with the anionic cardiolipin (Gonzalvez and Gottlieb, 2007)