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This minimizes waste while providing enough doses to complete the starting phase
However, this combination induced mesoderm formation in human PSCs probably due to the excessive level of Wnt signaling favoring mesoderm formation (Pan et al., 2022)
And this is possible through a mechanism working with collagen synthesis
[104] reported that P-15 alone is not capable of upregulating the proliferation and calcifying potential of human osteoblasts in vitro
