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However, in well identified groups of class III patients and, even more significantly, in the subgroup of class III HR patients, the use of a TreoFluT regimen was associated with significant improvements in survival and EFS, due to a significant decrease in the incidence of sinusoidal obstruction syndrome (SOS) [89]

Some peptides may require storage at -80C to prevent rapid degradation

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The consistency of the preclinical data across multiple studies and laboratories supports the mechanistic hypothesis