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Elevated homocysteine and aberrant FOCM have also been reported in Amyotrophic Lateral Sclerosis, Multiple Sclerosis, and Huntingtons disease and are associated with neuroinflammation, demyelination, neuronal loss, and severe disease phenotypes in these conditions
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393 Thus, the establishment and maintenance of polarity necessitates intricate crosstalk between Rho and Rac
