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At the tissue level, redox signaling pathways also regulate changes in the extracellular matrix and microenvironment, promoting the timely clearance of senescent cells and preventing the onset of human diseases

Landree LE, Hanlon AL, Strong DW, Rumbaugh G, Miller IM, Thupari JN, Connolly EC, Huganir RL, Richardson C, Witters LA, Kuhajda FP, Ronnett GV: C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism

H., Godinho B

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These results imply that ALK5 inhibitors could be promising therapeutic agents for treating fibrosis associated with endometriosis