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The medication undergoes proteolytic degradation, meaning enzymes break it down into smaller peptide fragments and amino acids before elimination

For instance, subjects with hypertriglyceridemia have increased numbers of sdLDL particles that are relatively poor in cholesterol and CE and rich in TG compared with subjects with normal TG

We also discuss the different HTAs evaluated in preclinical and clinical development and their potential impact as alternative or complementary therapeutic options to cure HCV infection and associated liver diseases

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