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Model Selection: In vitro: 3T3-L1 adipocytes, primary adipocytes Ex vivo: Adipose tissue explants In vivo: DIO models, body composition assessment 5

With a median movement-free endurance of roughly 8 months, the number of patients who can proceed with treatment for a very long time is small

PMID 30074676

Gastrointestinal effects: Concomitant use of diclofenac and prednisolone in the treatment of arthritis may provide additional therapeutic benefit and permit reduction of glucocorticoid dosage

In an attempt to make sense of all this, CBC spoke with Bob Hancock, a microbiologist at the University of British Columbia who studies infectious diseases and the immune system