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other allergic reactions that have been reported include erythema, skin rash (unspecified), pruritus, general malaise, and respiratory difficulty due to bronchospasm

doi: 10.1016/S1875-5364(14)60078-9

Involved in cellular signaling and regulating calcium levels, CD38 degrades NAD + , using it as a co-substrate for its enzymatic activity 135,136

Considering that some segments of the nephron are highly sensitive to oxygen variations, if the lung is injured it can cause severe hypoxemia which in time can reduce renal blood flow, contributing to renal impairment as well (Basu and Wheeler 2013)