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Standard protocols typically last 46 weeks based on injury severity

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It can bind directly to the heme iron of NOS to trigger various chemical and biochemical reactions (e.g., NO deoxygenation associated with scavenging of NO and vasoconstriction, as ob- served for hemolytic diseases [ 52 ], or S-nitrosylation of HbA hemoglobin responsible mainly for lung injury associated with an increased formation of red blood cells [ 53 ])

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