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As described previously, the major part of exogenous cystine is incorporated in GSH, yet unexpectedly, the remaining part is incorporated in co-enzyme A synthesis via the pantothenate pathway (69)

Therefore, a very important aspect of understanding how zinc can be used as a therapeutic agent is the necessity of a detailed understanding of the factors that influence zinc ion homeostasis and the optimization of the relevant concentrations

Histopathological evaluation and immunohistochemistry (IHC) Bouins fixative was used to fix the midbrain samples, followed by xylol clearing, graded alcohol dehydration, and paraffin embedding