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Even more intriguing is the fact that none of the inclusion criteria for the above-mentioned studies encompassed tumour markers to potentially discard any ongoing or potential tumour process that, obviously, IGF-1 could accelerate

According to the American Association of Clinical Endocrinologists the and American College of Endocrinology (AACE/ACE) Obesity Clinical Practice Guidelines, weight loss medications must not be used during pregnancy

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doi:10.2147/cia.S118152 Rassaf T, Rammos C, Hendgen-Cotta UB, et al

In a theoretical sense, if both mechanisms were operating simultaneously and both working at full effect, they would be complementary rather than redundant
