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However, all the intermediates involved in both AAA oxidation and reduction in Clostridium sporogenes were identified much later, and the enzymes responsible for the fermentation of phenylalanine (Dickert et al., 2000, 2002), as well as of tryptophan and tyrosine (Li, 2014) were characterized in detail

, Higgins, G

Conclusion Fatigue poses a substantial challenge for people with MS, affecting a large majority, with more than 50% of patients considering it their most disabling symptom

The third one is that the follow-up duration for these studies ranged from seven days to three years, which may result in potential publication bias and reduce the reliability of these trials

For example, a study that used dried leaf revealed a decrease in the frequency of migraines while another using a CO2 extract did not show significant benefit (Pittler 2004)