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rhamnosus , Bifidobacterium longum, and Saccharomyces boulardii improved sleep quality, anxiety, depression, and pain scores, while another group that received 10 grams of the prebiotic inulin had improved pain scores and sleep quality only

These results strongly suggest that gbh-1(G283R) and gbh-1(G247Vfs* 6) are functional alleles

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Severe BIPN can result in muscle atrophy, diminished ankle reflexes, and reduced proprioception, leading to foot drop, ataxia, and gait disturbances, all of which can impair daily functioning (Yamamoto and Egashira, 2021

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